Although most Americans have eschewed seasonal COVID-19 vaccines, the updated shots continue to show significant protection against cardiovascular disease, especially for those over age 75 and those with underlying medical conditions. That's according to a new study that pulled data from more than 1 million patients in a US Department of Veterans Affairs (VA) health system.

The finding builds on previous data showing that the vaccines significantly lower the risk of COVID-19-associated cardiovascular risks, particularly heart attacks and strokes. But it wasn't a given that the benefit would hold up over time—as the virus evolved, the vaccines were updated, population-level immunity increased from previous infection and vaccination, and risk of severe outcomes fell.

The new study, published in JAMA Internal Medicine, found that the 2024–2025 COVID-19 vaccine continued to protect against COVID-19-associated "major adverse cardiovascular events" (MACE), which include cardiovascular death, heart attack, stroke, and hospitalization for heart failure.

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For the first time, the American College of Obstetricians & Gynecologists (ACOG) has released its own recommendations for maternal vaccination, providing formal guidance that diverges from that of the Centers for Disease Control and Prevention amid unprecedented policy changes and meddling from anti-vaccine Health Secretary Robert F. Kennedy Jr.

ACOG President Camille Clare blamed "changing national recommendations coupled with rampant vaccine misinformation" for the confusion among patients and health care professionals about vaccines during pregnancy.

"It is incredibly important for the public to have access to reliable, evidence-based information on maternal immunizations from a trusted source. ACOG is proud to be that source," Clare said in a statement.

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